Serum Bone-Specific Alkaline Phosphatase as an indicator of the quantity of callus formation in mandibular fracture patients seen in a Nigerian Teaching Hospital

It is important to evaluate the level of bone-specific alkaline phosphatase as it relates quantity callus formed in mandibular fracture healing. The objective present study was assess Serum Bone-Specific Alkaline Phosphatase (BsALP) an indicator formation patients with and determine relationship between BsALP using two treatment methods. Fifty-five isolated fractures were enrolled. measured at presentation, 3rd 6th week. recruited into groups: Closed Reduction Mandibulomaxillary Fixation (MMF) Open Internal (ORIF). Callus Index week after digital postero-anterior view jaws on DICOM viewer software. mean value 26.2±9.5 ng/mL. concentration double site higher than those a single fracture, p=0.102. Peak serum observed post-intervention (28.1±8.2 ng/mL). Statistically significant differences week, presentation p<0.001, respectively. There no correlation 6 weeks (r=-0.08, p=0.580). MMF group had levels compared ORIF (p=0.14) (p=0.18). amount treated for fractures. Hence, could be used adjunct monitor healing